A study published in the Lancet Oncology, reported on data from over 25 000 women with endometrial cancer, finding that use of oral contraceptives reduces the risk of developing endometrial cancer. The study found that women who used oral contraceptives for the longest period of time had the greatest reduction in risk. The effects were reported to last for longer than 30 years after discontinuing the use of oral contraceptives. The researchers also found that oral contraceptive use was associated with a greater reduction in the risk of endometrial carcinomas, compared with endometrial sarcomas.
Collaborative Group on Epidemiological Studies on Endometrial Cancer “Endometrial cancer and oral contraceptives: an individual participant meta-analysis of 27 276 women with endometrial cancer from 36 epidemiological studies” The Lancet Oncology, Published Online: August 4, 2015.