1c\u00a0<\/sub>readings between 7% and 10%. The second trial had 53 women in the CGM group and 57 women in the control group.<\/li>\n<\/ul>\nThe participants in the continuous glucose monitoring groups were each given and educated on how to use a CGM system.<\/p>\n
Participants in the CGM and control groups were advised to measure capillary blood glucose readings at least seven times a day. In the pregnancy trial, HBA1c\u00a0<\/sub>was measured at baseline, 24 weeks gestation, and 34 weeks gestation.<\/p>\nIn the planning for the pregnancy trial, HBA1c\u00a0<\/sub>was measured at baseline, 12 weeks, and 24 weeks.<\/p>\nA final measurement was made at confirmation of a positive pregnancy test if a patient conceived before the 24-week mark.<\/p>\n
Newborn outcomes measured include preterm delivery, neonatal hypoglycemia requiring intravenous treatment, birthweight, intensive care admission for more than 24 hours, and birth injury.<\/p>\n
What could be found from the results of the study?<\/h3>\n\n- The results from the study show that the pregnant CGM participants spent more time within their glucose level targets and less time in hyperglycemic states.<\/li>\n
- There was also a slight decrease in HBA1c\u00a0<\/sub>when compared to the control group.<\/li>\n
- The health of newborns in the pregnant CGM group was significantly improved, based on the outcomes measured.<\/li>\n
- There was no significant difference in the planning for the pregnancy trial.<\/li>\n<\/ol>\n
The study indicates that continuous glucose monitoring in pregnant women with type 1 diabetes can be beneficial and helps improve the health of both the mother and newborn child. <\/strong><\/em><\/p>\nThis is the first study to demonstrate non-glycaemic positive health outcomes for CGM.<\/p>\n
This indicates that clinical care guidelines should be amended to include a recommendation that CGM should be offered to all pregnant women with type 1 diabetes.<\/p>\n<\/div><\/div>\n\n\n\n
\n\n\n\nWritten by Anuolu Bank-Oni, Pharm.D, CDE<\/p>\n\n\n\n
Reference:<\/p>\n\n\n\n
Feig D.S, et al \u201cContinuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial\u201d. The Lancet http:\/\/dx.doi.org\/10.1016\/S0140-6736(17)32400-5<\/p>\n","protected":false},"excerpt":{"rendered":"
According to current clinical care guidelines, women with type 1 diabetes should aim for optimal glucose control before and during pregnancy, as this significantly contributes to the health of both the mother and child. Nationwide UK data states that only 15% of pregnant women achieve their goal glycated hemoglobin (HBA1c) levels during early pregnancy. HBA1c\u00a0is […]<\/p>\n","protected":false},"author":1,"featured_media":2210,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"_links":{"self":[{"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/posts\/2204"}],"collection":[{"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/comments?post=2204"}],"version-history":[{"count":3,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/posts\/2204\/revisions"}],"predecessor-version":[{"id":2209,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/posts\/2204\/revisions\/2209"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/media\/2210"}],"wp:attachment":[{"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/media?parent=2204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/categories?post=2204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clinicaltrialscanada.com\/wp-json\/wp\/v2\/tags?post=2204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}